Macquarie University researchers targeted a protein known as disulphide isomerase (PDI), most commonly found in the gelatinous liquid (cytoplasm) of cells, where it helps guide other proteins into correct formation. However, the team discovered that PDI can move through the cytoplasm and into the cell's control center – the nucleus – to repair breaks in deoxyribonucleic acid (DNA) strands.
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A protein found in our cells has emerged as a secret weapon against biological aging, acting like a glue to repair damaged DNA and ward off neurological degeneration including that seen in motor neuron, Alzheimer’s and Parkinson’s diseases.
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