“Studies like ours show us that both family-based and genomic-based datasets are valuable in answering questions about how genetic and environmental influences change across the lifespan.”

As early as 7 months old, researchers assessed 7 measures of cognition, including vocalization, ability to stay on task, and “novelty preference” — whether the infants preferred to play with new toys over ones they were familiar with. Age-appropriate cognitive assessments have been done at five points, so far.The team found that looking at cognitive tests in infancy could predict about 13% of the variance in scores at age 30.Two measures —novelty preference and task orientation—were the strongest predictors. This early life “signal” is not huge, the authors note.

Infant Novelty Preference & Task Orientation And Adult Cognition

As expected, genes played a big role in influencing general cognitive ability, with genetic influences measured by age 7 accounting for about half of the variation in scores at age 30.But environment also had a significant and lasting impact.One of the most exciting findings was that 10% of the variability in adult cognitive ability was explained by environmental influences before year one or two. The older the children got, the more influence genes had and the less environment had.This suggests that even the pre-preschool environment matters.

Twins Say It’s Both, And Nurture Enters Early

Watching a baby babble, play and interact with others can provide useful insight into what their cognitive ability might be like decades later, according to new University of Colorado Boulder research published in the journal PNAS. The study of more than 1,000 twins found that tests as early as 7 months of age can help predict performance on cognitive measures at age 30. It also found that an infant’s environment plays a more significant role in shaping life-long cognition than scientists realized. It could even influence risk of dementia later in life, the authors said.

7 Months To 30 Years Ahead

Similar to “IQ,” general cognitive ability (GCA) is a single, composite measure of a person’s capacity to learn, reason, understand and problem-solve. Prior research has shown that much of our GCA is established by childhood. Give an 8-year-old a battery of tests to determine their GCA and their score will look remarkably similar at age 30. Measures of intelligence at age 20 are highly correlated with those at age 62, and IQ doesn’t change much between age 11 and 90.

General Cognitive Ability (GCA) Across Our Lifetime

To explore what role genetics vs. environment plays, the study compared GCA score differences between identical twins, who share 100% of their genes, and fraternal twins, who only share half of their genes. In general, if there is greater similarity among identical twins than fraternal twins, this suggests that genes play a strong role in that trait.

Nature, Nurture Or Both? What Do Twins Say?

Senior author Chandra Reynolds, who studies age-related diseases including Alzheimer’s and dementia, says the findings could have implications not only for how youth do in school or how adults perform at work but also how prone they may be to age-related cognitive decline.

Can Nurture In Infancy Affect Cognitive Decline In Old Age?

“There are thousands of genes that influence intelligence, so you are never going to find an ‘intelligence gene’, but we have found many with tiny effects that when put together can have an impact.”

The study also confirms that “polygenic scores” can be a useful tool.Polygenic scores are single numbers that aggregate a person’s genetic variants to estimate predisposition to a trait, like intelligence. For the study, the researchers used genetic data from nearly 1 million individuals gathered via large datasets like 23 and Me to give each of the adult twins a polygenic score based on their own DNA, for cognitive ability. Remarkably, the twins’ scores closely matched what would be expected based on their tests when they were babies.

A Polygenic Score For Intelligence

Few scientists however looked back further to see what — if anything—signals in infancy can tell us about cognition in adulthood and old age.Gustavson and senior author Chandra Reynolds, a professor of psychology and neuroscience, looked at data from 1,098 participants in the Colorado Longitudinal Twin Study. The university’s Institute of Behavioral Genetics (IBG) launched the study in 1985, enrolling baby twins from Colorado’s Front Range to assess the role that genes vs. environment play in various aspects of development.

GCA In Infancy, With The Help Of Twins

“We certainly do not want to imply that cognition is somehow fixed by seven months old. But the idea that a very simple test in infancy can help predict the results of a very complicated cognitive test taken 30 years later is exciting.”

Cognitive aging is a life-long process, not just something that begins in mid-life. It could be that certain interventions, like strong educational foundations in early life could help maximize what people are capable of and help them keep that cognitive gas in the tank for as long as possible.

A new study reveals that cognitive tests in infancy can modestly predict intelligence three decades later.

CHANDRA REYNOLDS

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